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Camotisita intermediate




1. Camoist (59721-16-3) Introduction
Chinese name: 4-(dimethylamino)-2-oxoethyl-2-(4-hydroxyphenyl)acetate
English name: 4-Hydroxybenzeneacetic Acid 2-(Dimethylamino)-2-Oxoethyl Ester
CAS RN:59721-16-3
Constitutional formula :

Formula: C12H15NO4
Molecular weight: 237.10
Melting point: 104-107℃
Appearance: white or white-like powder.
Use: Intermediate in the synthesis of camotisit (a drug for the treatment of pancreatitis).

2. Quality standards

project  metric bear fruit remarks
surface White or white-like powder White powder  
melting point ,℃ 104.0-107.0 105.3-106.2  
fineness ,% ≥99.0 99.85 LC. Chromatographic column: 25cm*4.5mm 5μm ODS;
Mobile phase: methanol-water-HAc (200/800/1, V/V);
UV: 235 nm; Sample: 25 mg/10 mL methanol; Injection volume: 5 μL.
loss on drying ,% ≤0.5 0.25  
       
MS(ESI),M+1 238.1 238.1  
NMR(1H, 13C) No significant peaks No significant peaks  






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